Brian Walker Selected Research

Neoplasms (Cancer)

12/2021	Chromosomal 1q21 abnormalities in multiple myeloma: a review of translational, clinical research, and therapeutic strategies.
7/2019	Ophthalmic Changes Following Maxillectomy With or Without Postoperative Radiation Therapy.
11/2018	A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea.
11/2013	Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization.
9/2013	Solid phase synthesis of Smac/DIABLO-derived peptides using a 'Safety-Catch' resin: identification of potent XIAP BIR3 antagonists.
6/2012	Antimicrobial/cytolytic peptides from the venom of the North African scorpion, Androctonus amoreuxi: biochemical and functional characterization of natural peptides and a single site-substituted analog.
6/2011	Proteasome inhibitors in cancer therapy.
10/2009	Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis.
5/2008	Proteasome inhibitors: a therapeutic strategy for haematological malignancy.
3/2008	Recombinant cathepsin S propeptide attenuates cell invasion by inhibition of cathepsin L-like proteases in tumor microenvironment.

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Brian Walker Research Topics

Disease

13	Neoplasms (Cancer) 12/2021 - 07/2003
6	Multiple Myeloma 01/2018 - 10/2003
5	Infections 01/2022 - 06/2011
4	Bacteremia 06/2020 - 01/2019
2	Asthma (Bronchial Asthma) 01/2022 - 03/2011
2	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2006
2	Carcinogenesis 12/2021 - 03/2008
2	Colorectal Neoplasms (Colorectal Cancer) 11/2013 - 10/2009
2	Hemolysis 06/2012 - 08/2009
2	Inflammation (Inflammations) 02/2012 - 03/2011
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 03/2009 - 12/2004
2	Astrocytoma (Pilocytic Astrocytoma) 08/2006 - 07/2003
1	Pathologic Processes 01/2022
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2022
1	Autoimmune Diseases (Autoimmune Disease) 12/2021
1	COVID-19 12/2021
1	Chromosome Aberrations (Chromosome Abnormalities) 12/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 06/2020
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 06/2020
1	Cross Infection (Nosocomial Infection) 04/2019
1	Urinary Tract Infections (Urinary Tract Infection) 04/2019
1	Ototoxicity 01/2019
1	Endocarditis 01/2019
1	Wounds and Injuries (Trauma) 01/2019
1	Lung Neoplasms (Lung Cancer) 11/2018
1	Horse Diseases (Horse Disease) 01/2018
1	Dyspnea (Shortness of Breath) 01/2017
1	Bronchiectasis 01/2017
1	Cystic Fibrosis (Mucoviscidosis) 01/2016
1	Breast Neoplasms (Breast Cancer) 09/2013
1	Gingivitis 02/2012
1	Cataract (Cataracts) 11/2009
1	Infertility (Sterility) 11/2009
1	Adenocarcinoma 10/2009
1	Obesity 08/2008
1	Atherosclerosis 08/2008
1	Glioblastoma (Glioblastoma Multiforme) 08/2006
1	Prostatic Neoplasms (Prostate Cancer) 06/2005
1	Neuroblastoma 01/2005
1	Alzheimer Disease (Alzheimer's Disease) 01/2005

Drug/Important Bio-Agent (IBA)

8	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 07/2003
8	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2018 - 10/2003
6	Peptides (Polypeptides)IBA 11/2018 - 01/2005
5	cathepsin SIBA 11/2013 - 07/2003
5	Proteasome InhibitorsIBA 06/2011 - 10/2003
4	Vancomycin FDA LinkGeneric 06/2020 - 01/2019
4	Cysteine Proteases (Cysteine Protease)IBA 10/2009 - 07/2003
3	Proteins (Proteins, Gene)FDA Link 10/2011 - 07/2002
2	Daptomycin FDA Link 06/2020 - 02/2020
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 02/2012
2	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2017 - 02/2012
2	Pancreatic Elastase (Elastase)IBA 01/2017 - 06/2011
2	Immunoglobulin G (IgG)IBA 03/2011 - 03/2008
2	CytokinesIBA 12/2004 - 07/2002
1	TrypsinIBA 01/2022
1	EnzymesIBA 01/2022
1	AutoantigensIBA 12/2021
1	AutoantibodiesIBA 12/2021
1	AntigensIBA 12/2021
1	Nucleocapsid ProteinsIBA 12/2021
1	Biocompatible Materials (Biomaterials)IBA 01/2019
1	gelatin methacryloylIBA 01/2019
1	GlucocorticoidsIBA 01/2018
1	ElastinIBA 01/2017
1	DesmosineIBA 01/2017
1	Epithelial Sodium ChannelsIBA 01/2016
1	Cathepsin GIBA 02/2012
1	Substance PIBA 02/2012
1	Biological ProductsIBA 02/2012
1	3-((aminoiminomethyl)thio)-2-propenoic acid (ZAPA)IBA 10/2011
1	Immunoglobulin A (IgA)IBA 10/2011
1	Metalloproteases (Metalloproteinases)IBA 06/2011
1	Virulence Factors (Pathogenicity Factors)IBA 06/2011
1	polycarbonateIBA 11/2009
1	Lidocaine (Xylocaine)FDA LinkGeneric 11/2009
1	EndotoxinsIBA 11/2009
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 11/2009
1	Cyclopentolate (Cyclogyl)FDA LinkGeneric 11/2009
1	Tropicamide FDA LinkGeneric 11/2009
1	Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA 01/2009
1	Protein Isoforms (Isoforms)IBA 01/2009
1	Immunoglobulins (Immunoglobulin)IBA 01/2009
1	Cysteine (L-Cysteine)FDA Link 03/2008
1	CathepsinsIBA 03/2008
1	Cathepsin LIBA 03/2008
1	ParaffinIBA 08/2006
1	fibroblast activation protein alphaIBA 07/2006
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 06/2006
1	Bortezomib (Velcade)FDA Link 06/2006
1	AndrogensIBA 06/2005
1	Serine Proteases (Serine Protease)IBA 06/2005
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 06/2005
1	Amyloid beta-PeptidesIBA 01/2005
1	lactacystinIBA 01/2005
1	Glyoxal (Ethanedial)IBA 01/2005
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2005
1	leucyl-leucyl-leucineIBA 01/2005

Therapy/Procedure

5	Therapeutics 01/2018 - 06/2006
1	Drug Therapy (Chemotherapy) 12/2021
1	Adjuvant Radiotherapy 07/2019